Symbol Name ID |
Egln1
egl-9 family hypoxia-inducible factor 1 MGI:1932286 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | cardiovascular system phenotype |
abnormal blood vessel morphology |
abnormal capillary morphology |
abnormal capillary branching pattern |
abnormal kidney vasculature morphology |
abnormal liver vasculature morphology |
dilated liver sinusoidal space |
liver vascular congestion |
abnormal lung vasculature morphology |
pulmonary vascular congestion |
increased angiogenesis |
blood vessel congestion |
dilated vasculature |
abnormal myocardium layer morphology |
increased myocardial fiber size |
myocardial fiber degeneration |
abnormal trabecula carnea morphology |
thin ventricle myocardium compact layer |
delayed heart development |
abnormal heart morphology |
abnormal coronary vessel morphology |
increased heart atrium size |
abnormal interventricular septum morphology |
increased heart weight |
enlarged heart |
abnormal heart ventricle morphology |
abnormal heart left ventricle morphology |
cardiac interstitial fibrosis |
dilated cardiomyopathy |
abnormal blood viscosity |
hypervolemia |
cardiac ischemia |
hemorrhage |
decreased ventricle muscle contractility |
decreased cardiomyocyte apoptosis |
abnormal response of heart to induced stress |
increased response of heart to induced stress |
abnormal response to cardiac infarction |
decreased myocardial infarct size |
congestive heart failure |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||||
Egln1Gt(RRG405)Byg/Egln1Gt(RRG405)Byg | * | ||||||||||||||||||||||||||||||||||||||||
Egln1tm1Fong/Egln1tm1Fong | |||||||||||||||||||||||||||||||||||||||||
Egln1tm1.1Brei/Egln1tm1.1Brei Myl2tm1(cre)Krc/Myl2+ (conditional) |
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Egln1tm1.1Brei/Egln1tm1.1Brei Tg(CD68-icre)1Bwlx/0 (conditional) |
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Egln1tm1Kael/Egln1tm1Kael Tg(CAG-cre/Esr1*)5Amc/0 (conditional) |
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Egln1tm1Kael/Egln1tm1Kael Tg(Myh6-cre)2182Mds/0 (conditional) |
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Egln1tm2.1Fsl/Egln1tm2.1Fsl Pax3tm1(cre)Joe/Pax3+ (conditional) |
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Egln1tm2.1Fsl/Egln1tm2.1Fsl Tg(Cdh5-cre)7Mlia/0 (conditional) |
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Egln1tm2Fong/Egln1tm2Fong Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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